The Sixers will open up the 2013-14 season against the Miami Heat at home on October 30.
- October 30 vs Miami Heat – Match up against the defending Eastern Conference and NBA champions
- November 11 vs San Antonio Spurs – Match up against the defending Western Conference champions
- November 13 vs Houston Rockets – First look at Dwight Howard as a Rocket
- November 29 vs New Orleans Pelicans – Jrue Holiday returns to Philadelphia for the first time
- December 12 vs Brooklyn Nets – First look at Paul Pierce and Kevin Garnett in their new uniforms